Amniosin™ is a cryopreserved acellular human amniotic membrane-derived biological dressing. Due to containing of different biological factors, Amniosin™ has an important reconstructive role as a biological dressing.
Amniosin™ has proved to provide two elements to the chronic wound repair process:
1. Supply of different bioactive extracellular matrix components such as collagen, Fibronectin, Laminin, Proteoglycan and glycosaminoglycan.
2. Function as a permissive, performed, normal human matrix for keratinocyte and fibroblast migration and proliferation.
Indications and Clinical use:
Amniosin™ has been demonstrated in clinics for Corneal and conjunctival diseases:
Observed Clinical Effects:
- Facilitate epithelialization
- Reduce vascularization
- Maintain normal epithelial phenotype
- Reduce scarring
- Reduce inflammation
As a graft for corneal diseases:
- Persistent corneal epithelial defect with or without ulceration
- Painful bullous keratopathy with erosion
- Stevens- Johnson syndrome & Toxic Epidermal Necrolysis
- Partial limbal stem cell deficiency
- Chemical burns
- Sterile corneal stromal thinning descemetocele & perforation
- Band keratopathy, scar or tumor